Anti-Acetyl CoA synthetase Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90017-50, BS90017-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9NR19

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF

All Applications: WB:1:1,000
ICC:1:50-1:200

Background: ACSS2 (acyl-CoA synthetase short-chain family member 2), also known as ACAS2, ACS, ACSA or AceCS, is a 701 amino acid cytoplasmic protein that belongs to the ATP-dependent AMP-binding enzyme family. Existing as a monomer, ACSS2 functions to catalyze the ATP-dependent activation of acetate, a reaction that yields acetyl-CoA for use in energy generation and lipid synthesis. ACSS2 expression, which is highest in liver and kidney tissue, is regulated by the presence of unsaturated fatty acids and sterol regulatory element-binding proteins (SREBPs). Human ACSS2 exists as two alternatively spliced isoforms and shares 93% sequence identity with its mouse counterpart, suggesting a conserved role between species.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: ACS polyclonal antibody detects endogenous levels of ACS protein.

Bioworld Molecular Weight: ~ 79 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining Acetyl CoA synthetase in RH-35 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining Acetyl CoA synthetase in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: ACS, AceCS, ACSS2, ACAS2, AceCS, Acetate CoA ligase, Acetate thiokinase, AcetateCoA ligase, Acetyl CoA synthetase, Acetyl Coenzyme A synthetase 2 (ADP forming), Acetyl coenzyme A synthetase cytoplasmic, Acetyl-CoA synthetase, Acetyl-coenzyme A synthetase, ACS, ACSA, ACSA, ACSS2, Acyl activating enzyme, Acyl CoA synthetase short chain family member 2, Acyl-activating enzyme, Acyl-CoA synthetase short-chain family member 2, Cytoplasmic acetyl coenzyme A synthetase, cytoplasmic, MYH7B,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Acetylated